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Small molecule-mediated up-regulation of microRNA targeting a key cell death modulator BNIP3 improves cardiac function following ischemic injury

Genetic ablation of BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3), an essential regulator of cardiac cell death, is an effective way to prevent cardiac cell death triggered by pathologic conditions. However, currently there exists no known means, such as inhibitors, to down-regula...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Lee, Se-Yeon, Lee, Seahyoung, Choi, Eunhyun, Ham, Onju, Lee, Chang Youn, Lee, Jiyun, Seo, Hyang-Hee, Cha, Min-Ji, Mun, Bohyun, Lee, Yunmi, Yoon, Cheesoon, Hwang, Ki-Chul
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806297/
https://ncbi.nlm.nih.gov/pubmed/27008992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23472
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