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Suppression of miR-181a attenuates H(2)O(2)-induced death of mesenchymal stem cells by maintaining hexokinase II expression
BACKGROUND: Low survival rate of transplanted cells compromises the efficacy of cell therapy. Hexokinase II (HKII) is known to have anti-apoptotic activity through its interaction with mitochondria. The objective was to identify miRNAs targeting HKII and investigate whether miRNA-mediated modulation...
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發表在: | Biol Res |
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Main Authors: | , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
BioMed Central
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539679/ https://ncbi.nlm.nih.gov/pubmed/26283227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-015-0036-5 |
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