Suppression of miR-181a attenuates H(2)O(2)-induced death of mesenchymal stem cells by maintaining hexokinase II expression

BACKGROUND: Low survival rate of transplanted cells compromises the efficacy of cell therapy. Hexokinase II (HKII) is known to have anti-apoptotic activity through its interaction with mitochondria. The objective was to identify miRNAs targeting HKII and investigate whether miRNA-mediated modulation...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Res
Hauptverfasser: Lee, Seahyoung, Yun, Ina, Ham, Onju, Lee, Se-Yeon, Lee, Chang Yeon, Park, Jun-Hee, Lee, Jiyun, Seo, Hyang-Hee, Choi, Eunhyun, Hwang, Ki-Chul
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539679/
https://ncbi.nlm.nih.gov/pubmed/26283227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-015-0036-5
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