let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3

INTRODUCTION: Mesenchymal stem cells (MSCs) have therapeutic potential for the repair of myocardial injury. The efficacy of MSC therapy for myocardial regeneration mainly depends on the survival of cells after transplantation into the infarcted heart. In the transplanted regions, reactive oxygen spe...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Ham, Onju, Lee, Se-Yeon, Lee, Chang Youn, Park, Jun-Hee, Lee, Jiyun, Seo, Hyang-Hee, Cha, Min-Ji, Choi, Eunhyun, Kim, Soonhag, Hwang, Ki-Chul
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546263/
https://ncbi.nlm.nih.gov/pubmed/26296645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0134-x
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