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Characterization of the metabolism of benzaldehyde dimethane sulfonate (NSC 281612, DMS612)
INTRODUCTION: Benzaldehyde dimethane sulfonate (BEN, DMS612, NSC281612) is a bifunctional alkylating agent currently in clinical trials. We previously characterized the degradation products of BEN in plasma and blood. The conversion of BEN to its carboxylic acid analogue (BA) in whole blood, but not...
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| Veröffentlicht in: | Cancer Chemother Pharmacol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545378/ https://ncbi.nlm.nih.gov/pubmed/26193988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2828-2 |
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