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Characterization of the metabolism of benzaldehyde dimethane sulfonate (NSC 281612, DMS612)
INTRODUCTION: Benzaldehyde dimethane sulfonate (BEN, DMS612, NSC281612) is a bifunctional alkylating agent currently in clinical trials. We previously characterized the degradation products of BEN in plasma and blood. The conversion of BEN to its carboxylic acid analogue (BA) in whole blood, but not...
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| Publicat a: | Cancer Chemother Pharmacol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545378/ https://ncbi.nlm.nih.gov/pubmed/26193988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2828-2 |
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