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Characterization of the metabolism of benzaldehyde dimethane sulfonate (NSC 281612, DMS612)
INTRODUCTION: Benzaldehyde dimethane sulfonate (BEN, DMS612, NSC281612) is a bifunctional alkylating agent currently in clinical trials. We previously characterized the degradation products of BEN in plasma and blood. The conversion of BEN to its carboxylic acid analogue (BA) in whole blood, but not...
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| Publicado no: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545378/ https://ncbi.nlm.nih.gov/pubmed/26193988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2828-2 |
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