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AML sensitivity to YM155 is modulated through AKT and Mcl-1
HL60 and U937 (acute myeloid leukemia (AML) cell lines) were assessed for sensitivity to YM155, and found to have distinct sensitive and resistant phenotypes, respectively. In HL60 cells, YM155 inhibition of growth proliferation was due to apoptosis which was measured by annexin V/PI staining. YM155...
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| Publicado no: | Cancer Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545294/ https://ncbi.nlm.nih.gov/pubmed/26118775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.05.034 |
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