Aberrant splicing and drug resistance in AML

The advent of next-generation sequencing technologies has unveiled a new window into the heterogeneity of acute myeloid leukemia (AML). In particular, recurrent mutations in spliceosome machinery and genome-wide aberrant splicing events have been recognized as a prominent component of this disease....

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: de Necochea-Campion, Rosalia, Shouse, Geoffrey P., Zhou, Qi, Mirshahidi, Saied, Chen, Chien-Shing
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018179/
https://ncbi.nlm.nih.gov/pubmed/27613060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0315-9
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