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Aberrant RNA Splicing in Cancer and Drug Resistance

More than 95% of the 20,000 to 25,000 transcribed human genes undergo alternative RNA splicing, which increases the diversity of the proteome. Isoforms derived from the same gene can have distinct and, in some cases, opposing functions. Accumulating evidence suggests that aberrant RNA splicing is a...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Wang, Bi-Dar, Lee, Norman H.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266310/
https://ncbi.nlm.nih.gov/pubmed/30463359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10110458
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