Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Clinical challenges exist in reducing prostate cancer (PCa) disparities. The RNA splicing landscape of PCa across racial populations has not been fully explored as a potential molecular mechanism contributing to race-related tumour aggressiveness. Here, we identify novel genome-wide, race-specific R...

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Publicado no:Nat Commun
Main Authors: Wang, Bi-Dar, Ceniccola, Kristin, Hwang, SuJin, Andrawis, Ramez, Horvath, Anelia, Freedman, Jennifer A., Olender, Jacqueline, Knapp, Stefan, Ching, Travers, Garmire, Lana, Patel, Vyomesh, Garcia-Blanco, Mariano A., Patierno, Steven R., Lee, Norman H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497057/
https://ncbi.nlm.nih.gov/pubmed/28665395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15921
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