A Novel FGFR3 Splice Variant Preferentially Expressed in African American Prostate Cancer Drives Aggressive Phenotypes and Docetaxel Resistance

Alternative splicing (AS) has been shown to participate in prostate cancer (PCa) development and progression; however, a link between AS and PCa health disparities has been largely unexplored. Here we report on the cloning of a novel splice variant of FGFR3 that is preferentially expressed in Africa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer Res
Prif Awduron: Olender, Jacqueline, Wang, Bi-Dar, Ching, Travers, Garmire, Lana X., Garofano, Kaitlin, Ji, Youngmi, Knox, Tessa, Latham, Patricia, Nguyen, Kenneth, Rhim, Johng, Lee, Norman H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886680/
https://ncbi.nlm.nih.gov/pubmed/31266816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0415
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