A Novel FGFR3 Splice Variant Preferentially Expressed in African American Prostate Cancer Drives Aggressive Phenotypes and Docetaxel Resistance

Alternative splicing (AS) has been shown to participate in prostate cancer (PCa) development and progression; however, a link between AS and PCa health disparities has been largely unexplored. Here we report on the cloning of a novel splice variant of FGFR3 that is preferentially expressed in Africa...

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Pubblicato in:Mol Cancer Res
Autori principali: Olender, Jacqueline, Wang, Bi-Dar, Ching, Travers, Garmire, Lana X., Garofano, Kaitlin, Ji, Youngmi, Knox, Tessa, Latham, Patricia, Nguyen, Kenneth, Rhim, Johng, Lee, Norman H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886680/
https://ncbi.nlm.nih.gov/pubmed/31266816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0415
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