Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1

The inhibitor-of-apoptosis family member survivin has been reported to inhibit apoptosis and regulate mitosis and cytokinesis. In multiple myeloma, survivin has been described to be involved in downstream sequelae of various therapeutic agents. We assessed 1093 samples from previously untreated pati...

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Udgivet i:Oncotarget
Main Authors: Wagner, Verena, Hose, Dirk, Seckinger, Anja, Weiz, Ludmila, Meißner, Tobias, Rème, Thiery, Breitkreutz, Iris, Podar, Klaus, Ho, Anthony D., Goldschmidt, Hartmut, Krämer, Alwin, Klein, Bernard, Raab, Marc S.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
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Priority Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279369/
https://ncbi.nlm.nih.gov/pubmed/25296978
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