Emerging Effects of Sepantronium Bromide (YM155) on MOLT-4 Cell Line Apoptosis Induction and Expression of Critical Genes Involved in Apoptotic Pathways

Purpose: Sepantronium bromide (YM155) is a Survivin inhibitor which recently advanced as an anticancer agent in phase II clinical trials. Survivin belongs to IAP (inhibitor of apoptosis) gene family and is a pivotal target for treatment due to its overexpression and oncogenic function in many malign...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Shojaei Moghadam, Kobra, Farshdousti Hagh, Majid, Alivand, Mohammad Reza, Fardi, Masoumeh, Movassaghpour, Ali Akbar, Mohammadi, Ali, Moghadasi, Maryam, Solali, Saeed
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983994/
https://ncbi.nlm.nih.gov/pubmed/32002365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2020.010
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