Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1

The inhibitor-of-apoptosis family member survivin has been reported to inhibit apoptosis and regulate mitosis and cytokinesis. In multiple myeloma, survivin has been described to be involved in downstream sequelae of various therapeutic agents. We assessed 1093 samples from previously untreated pati...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wagner, Verena, Hose, Dirk, Seckinger, Anja, Weiz, Ludmila, Meißner, Tobias, Rème, Thiery, Breitkreutz, Iris, Podar, Klaus, Ho, Anthony D., Goldschmidt, Hartmut, Krämer, Alwin, Klein, Bernard, Raab, Marc S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279369/
https://ncbi.nlm.nih.gov/pubmed/25296978
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