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HCN1 Channels Contribute to the Effects of Amnesia and Hypnosis But Not Immobility of Volatile Anesthetics

BACKGROUND: HCN1 channels have been identified as targets of ketamine to produce hypnosis. Volatile anesthetics also inhibit HCN1 channels. However, the effects of HCN1 channels on volatile anesthetics in vivo is still elusive. This study uses global and conditional HCN1 knockout mice to evaluate ho...

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Detalhes bibliográficos
Publicado no:Anesth Analg
Main Authors: Zhou, Cheng, Liang, Peng, Liu, Jin, Ke, Bowen, Wang, Xiaojia, Li, Fengshan, Li, Tao, Bayliss, Douglas A., Chen, Xiangdong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544830/
https://ncbi.nlm.nih.gov/pubmed/26287296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000000830
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