Direct Activation of Sleep-Promoting VLPO Neurons by Volatile Anesthetics Contributes to Anesthetic Hypnosis

BACKGROUND: Despite seventeen decades of continuous clinical use, the neuronal mechanisms through which volatile anesthetics act to produce unconsciousness remain obscure. One emerging possibility is that anesthetics exert their hypnotic effects by hijacking endogenous arousal circuits. A key sleep-...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Moore, Jason T, Chen, Jingqiu, Han, Bo, Meng, Qing Cheng, Veasey, Sigrid C, Beck, Sheryl G, Kelz, Max B
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628836/
https://ncbi.nlm.nih.gov/pubmed/23103189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.08.042
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