Direct Activation of Sleep-Promoting VLPO Neurons by Volatile Anesthetics Contributes to Anesthetic Hypnosis

BACKGROUND: Despite seventeen decades of continuous clinical use, the neuronal mechanisms through which volatile anesthetics act to produce unconsciousness remain obscure. One emerging possibility is that anesthetics exert their hypnotic effects by hijacking endogenous arousal circuits. A key sleep-...

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Autors principals: Moore, Jason T, Chen, Jingqiu, Han, Bo, Meng, Qing Cheng, Veasey, Sigrid C, Beck, Sheryl G, Kelz, Max B
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628836/
https://ncbi.nlm.nih.gov/pubmed/23103189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.08.042
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