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HCN1 Channels Contribute to the Effects of Amnesia and Hypnosis But Not Immobility of Volatile Anesthetics

BACKGROUND: HCN1 channels have been identified as targets of ketamine to produce hypnosis. Volatile anesthetics also inhibit HCN1 channels. However, the effects of HCN1 channels on volatile anesthetics in vivo is still elusive. This study uses global and conditional HCN1 knockout mice to evaluate ho...

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書誌詳細
出版年:Anesth Analg
主要な著者: Zhou, Cheng, Liang, Peng, Liu, Jin, Ke, Bowen, Wang, Xiaojia, Li, Fengshan, Li, Tao, Bayliss, Douglas A., Chen, Xiangdong
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544830/
https://ncbi.nlm.nih.gov/pubmed/26287296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000000830
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