Direct Activation of Sleep-Promoting VLPO Neurons by Volatile Anesthetics Contributes to Anesthetic Hypnosis

BACKGROUND: Despite seventeen decades of continuous clinical use, the neuronal mechanisms through which volatile anesthetics act to produce unconsciousness remain obscure. One emerging possibility is that anesthetics exert their hypnotic effects by hijacking endogenous arousal circuits. A key sleep-...

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Autori principali: Moore, Jason T, Chen, Jingqiu, Han, Bo, Meng, Qing Cheng, Veasey, Sigrid C, Beck, Sheryl G, Kelz, Max B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628836/
https://ncbi.nlm.nih.gov/pubmed/23103189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.08.042
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