Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants

Most genome-wide methylation studies (EWAS) of multifactorial disease traits use targeted arrays or enrichment methodologies preferentially covering CpG-dense regions, to characterize sufficiently large samples. To overcome this limitation, we present here a new customizable, cost-effective approach...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Allum, Fiona, Shao, Xiaojian, Guénard, Frédéric, Simon, Marie-Michelle, Busche, Stephan, Caron, Maxime, Lambourne, John, Lessard, Julie, Tandre, Karolina, Hedman, Åsa K., Kwan, Tony, Ge, Bing, Rönnblom, Lars, McCarthy, Mark I., Deloukas, Panos, Richmond, Todd, Burgess, Daniel, Spector, Timothy D., Tchernof, André, Marceau, Simon, Lathrop, Mark, Vohl, Marie-Claude, Pastinen, Tomi, Grundberg, Elin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544751/
https://ncbi.nlm.nih.gov/pubmed/26021296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8211
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki