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Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
Most genome-wide methylation studies (EWAS) of multifactorial disease traits use targeted arrays or enrichment methodologies preferentially covering CpG-dense regions, to characterize sufficiently large samples. To overcome this limitation, we present here a new customizable, cost-effective approach...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4544751/ https://ncbi.nlm.nih.gov/pubmed/26021296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8211 |
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