Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes.

Human T lymphocytes can be activated through either the antigen/MHC receptor complex T3-Ti (CD3-Ti) or the T11 (CD2) molecule to proliferate via an IL-2 dependent mechanism. To investigate the relationship of these pathways to one another, we generated and characterized Jurkat mutants which selectiv...

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Autores principales: Alcover, A, Alberini, C, Acuto, O, Clayton, L K, Transy, C, Spagnoli, G C, Moingeon, P, Lopez, P, Reinherz, E L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC454469/
https://ncbi.nlm.nih.gov/pubmed/2901344
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