CD3 zeta dependence of the CD2 pathway of activation in T lymphocytes and natural killer cells.

In T lymphocytes, signal transduction through the CD2 adhesion molecule requires surface expression of the CD3-Ti T-cell receptor (TCR) complex. In contrast, in natural killer (NK) cells, CD2 functions in the absence of a TCR. Because the TCR on T lymphocytes and the CD16 low-affinity IgG Fc recepto...

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Autors principals: Moingeon, P, Lucich, J L, McConkey, D J, Letourneur, F, Malissen, B, Kochan, J, Chang, H C, Rodewald, H R, Reinherz, E L
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC48477/
https://ncbi.nlm.nih.gov/pubmed/1346934
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