Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes.

Human T lymphocytes can be activated through either the antigen/MHC receptor complex T3-Ti (CD3-Ti) or the T11 (CD2) molecule to proliferate via an IL-2 dependent mechanism. To investigate the relationship of these pathways to one another, we generated and characterized Jurkat mutants which selectiv...

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Sparad:
Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Alcover, A, Alberini, C, Acuto, O, Clayton, L K, Transy, C, Spagnoli, G C, Moingeon, P, Lopez, P, Reinherz, E L
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1988
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454469/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2901344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03035.x
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