Mobility of the human T lymphocyte surface molecules CD3, CD4, and CD8: regulation by a cAMP-dependent pathway.

The present study was undertaken to determine whether a cAMP pathway mediates the mobility of CD3, CD4, and CD8 within the membrane. Crosslinking CD3, CD4, and CD8 with monoclonal antibody and anti-antibody induced rapid accumulation of intracellular cAMP, occupancy of cAMP receptors, and was tempor...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kammer, G M, Boehm, C A, Rudolph, S A, Schultz, L A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279641/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.3.792
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