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The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway

Activated Toll-like receptors (TLRs) cluster in lipid rafts and induce pro- and anti-tumor responses. The organization of the assembly is critical to the understanding of how these key receptors control major signaling pathways in the cell. Although several models for individual interactions were pr...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Guven-Maiorov, Emine, Keskin, Ozlem, Gursoy, Attila, VanWaes, Carter, Chen, Zhong, Tsai, Chung-Jung, Nussinov, Ruth
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544004/
https://ncbi.nlm.nih.gov/pubmed/26293885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13128
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