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A Structural View of Negative Regulation of the Toll-like Receptor-Mediated Inflammatory Pathway
Even though the Toll-like receptor (TLR) pathway is integral to inflammatory defense mechanisms, its excessive signaling may be devastating. Cells have acquired a cascade of strategies to regulate TLR signaling by targeting protein-protein interactions, or ubiquitin chains, but the details of the in...
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Publicado no: | Biophys J |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576153/ https://ncbi.nlm.nih.gov/pubmed/26276688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.048 |
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