Head and neck cancers promote an inflammatory transcriptome through co-activation of classical and alternative NF-κB pathways

Head and neck squamous cell carcinomas (HNSCC) promote inflammation in the tumor microenvironment through aberrant NF-κB activation, but the genomic alterations and pathway networks that modulate NF-κB signaling have not been fully dissected. Here, we analyzed genome and transcriptome alterations of...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Yang, Xinping, Cheng, Hui, Chen, Jianhong, Wang, Ru, Saleh, Anthony, Si, Han, Lee, Steven, Guven-Maiorov, Emine, Keskin, Ozlem, Gursoy, Attila, Nussinov, Ruth, Fang, Jugao, Van Waes, Carter, Chen, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941750/
https://ncbi.nlm.nih.gov/pubmed/31624067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0832
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