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The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway

Activated Toll-like receptors (TLRs) cluster in lipid rafts and induce pro- and anti-tumor responses. The organization of the assembly is critical to the understanding of how these key receptors control major signaling pathways in the cell. Although several models for individual interactions were pr...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Guven-Maiorov, Emine, Keskin, Ozlem, Gursoy, Attila, VanWaes, Carter, Chen, Zhong, Tsai, Chung-Jung, Nussinov, Ruth
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544004/
https://ncbi.nlm.nih.gov/pubmed/26293885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13128
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