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The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway

Activated Toll-like receptors (TLRs) cluster in lipid rafts and induce pro- and anti-tumor responses. The organization of the assembly is critical to the understanding of how these key receptors control major signaling pathways in the cell. Although several models for individual interactions were pr...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Guven-Maiorov, Emine, Keskin, Ozlem, Gursoy, Attila, VanWaes, Carter, Chen, Zhong, Tsai, Chung-Jung, Nussinov, Ruth
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544004/
https://ncbi.nlm.nih.gov/pubmed/26293885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13128
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