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Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function in vivo
BACKGROUND: Voltage-gated Na(+) channels (Na(v)) are essential for myocyte membrane excitability and cardiac function. Na(v) current (I(Na)) is a large amplitude, short duration “spike” generated by rapid channel activation followed immediately by inactivation. However, even under normal conditions,...
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| Опубликовано в: : | Circulation |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4543581/ https://ncbi.nlm.nih.gov/pubmed/26187182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.015218 |
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