Curcumin effectively inhibits oncogenic NF-kB signaling and restrains stemness features in liver cancer

BACKGROUND & AIMS: The cancer stem cells (CSCs) have important therapeutic implications for multi-resistant cancers including hepatocellular carcinoma (HCC). Among the key pathways frequently activated in liver CSCs is NF-kB signaling. METHODS: We evaluated the CSCs-depleting potential of NF-kB...

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Veröffentlicht in:J Hepatol
Hauptverfasser: Marquardt, Jens U., Gomez-Quiroz, Luis, Camacho, Lucrecia O. Arreguin, Pinna, Federico, Lee, Yun-Han, Kitade, Mitsuteru, Domínguez, Mayrel Palestino, Castven, Darko, Breuhahn, Kai, Conner, Elizabeth A., Galle, Peter R., Andersen, Jesper B., Factor, Valentina M., Thorgeirsson, Snorri S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543531/
https://ncbi.nlm.nih.gov/pubmed/25937435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.04.018
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