Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis

An R120G missense mutation in the small heat shock protein α-B-crystallin (CryAB(R120G)) causes desmin-related cardiomyopathy (DRM). DRM is characterized by the formation of aggregates containing CryAB and desmin, and it can be recapitulated in transgenic mice by cardiac-specific expression of the m...

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Bibliografiska uppgifter
Huvudupphovsmän: Sanbe, Atsushi, Osinska, Hanna, Saffitz, Jeffrey E., Glabe, Charles G., Kayed, Rakez, Maloyan, Alina, Robbins, Jeffrey
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2004
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC454177/
https://ncbi.nlm.nih.gov/pubmed/15220483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401900101
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