Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy

Amyloid oligomers, similar to the toxic entities found in Alzheimer's disease patients and in other amyloid-based diseases, are present in cardiomyocytes derived from human heart-failure patients and in animal models of desmin-related cardiomyopathy (DRM). The R120G mutation in α-B-crystallin (...

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Главные авторы: Sanbe, Atsushi, Osinska, Hanna, Villa, Chet, Gulick, James, Klevitsky, Raisa, Glabe, Charles G., Kayed, Rakez, Robbins, Jeffrey
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224623/
https://ncbi.nlm.nih.gov/pubmed/16155124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503324102
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