Lanean...

Glutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian Failure

Glutathione (GSH) is the one of the most abundant intracellular antioxidants. Mice lacking the modifier subunit of glutamate cysteine ligase (Gclm), the rate-limiting enzyme in GSH synthesis, have decreased GSH. Our prior work showed that GSH plays antiapoptotic roles in ovarian follicles. We hypoth...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Endocrinology
Egile Nagusiak: Lim, Jinhwan, Nakamura, Brooke N., Mohar, Isaac, Kavanagh, Terrance J., Luderer, Ulrike
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541624/
https://ncbi.nlm.nih.gov/pubmed/26083875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1206
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!