Glutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian Failure

Glutathione (GSH) is the one of the most abundant intracellular antioxidants. Mice lacking the modifier subunit of glutamate cysteine ligase (Gclm), the rate-limiting enzyme in GSH synthesis, have decreased GSH. Our prior work showed that GSH plays antiapoptotic roles in ovarian follicles. We hypoth...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Lim, Jinhwan, Nakamura, Brooke N., Mohar, Isaac, Kavanagh, Terrance J., Luderer, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541624/
https://ncbi.nlm.nih.gov/pubmed/26083875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1206
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados