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Inhibition of hedgehog signaling reduces the side population in human malignant mesothelioma cell lines

Deregulation of crucial embryonic pathways, including hedgehog signaling, has been frequently implicated in a variety of human cancers and is emerging as an important target for anticancer therapy. This study evaluated the potential anticancer effects of cyclopamine, a chemical inhibitor of hedgehog...

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Detalles Bibliográficos
Publicado en:Cancer Gene Ther
Main Authors: Kim, H-A, Kim, M-C, Kim, N-Y, Kim, Y
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541142/
https://ncbi.nlm.nih.gov/pubmed/26206198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2015.31
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