Mutational Analysis of Hedgehog Signaling Pathway Genes in Human Malignant Mesothelioma

BACKGROUND: The Hedgehog (HH) signaling pathway is critical for embryonic development and adult homeostasis. Recent studies have identified regulatory roles for this pathway in certain cancers with mutations in the HH pathway genes. The extent to which mutations of the HH pathway genes are involved...

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Main Authors: Lim, Chuan Bian, Prêle, Cecilia M., Cheah, Hui Min, Cheng, Yuen Yee, Klebe, Sonja, Reid, Glen, Watkins, D. Neil, Baltic, Svetlana, Thompson, Philip J., Mutsaers, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691204/
https://ncbi.nlm.nih.gov/pubmed/23826113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066685
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