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An Integrated Analysis of the Genome-Wide Profiles of DNA Methylation and mRNA Expression Defining the Side Population of a Human Malignant Mesothelioma Cell Line

Intratumoral heterogeneity is a hallmark of all cancers and functions as the major barrier against effective cancer therapy. In contrast to genetic mutations, the role of epigenetic modifications in the generation and maintenance of heterogeneous cancer cells remains largely undetermined. This study...

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Pubblicato in:J Cancer
Autori principali: Kim, Myung-Chul, Kim, Na-Yon, Seo, Yu-Ri, Kim, Yongbaek
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039388/
https://ncbi.nlm.nih.gov/pubmed/27698904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15423
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