Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors

Allosteric modulators of G protein-coupled receptors (GPCRs), which target at allosteric sites, have significant advantages against the corresponding orthosteric compounds including higher selectivity, improved chemical tractability or physicochemical properties, and reduced risk of receptor oversen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:AAPS J
Egile Nagusiak: Feng, Zhiwei, Hu, Guanxing, Ma, Shifan, Xie, Xiang-Qun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer US 2015
Gaiak:
Review Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540734/
https://ncbi.nlm.nih.gov/pubmed/25940084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9776-y
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