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Allosteric Modulation of G Protein Coupled Receptors by Cytoplasmic, Transmembrane and Extracellular Ligands

G protein coupled receptors (GPCRs) bind diverse classes of ligands, and depending on the receptor, these may bind in their transmembrane or the extracellular domains, demonstrating the principal ability of GPCRs to bind ligand in either domains. Most recently, it was also observed that small molecu...

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Bibliographic Details
Main Authors: Yanamala, Naveena, Klein-Seetharaman, Judith
Format: Artigo
Language:Inglês
Published: MDPI 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760430/
https://ncbi.nlm.nih.gov/pubmed/24009470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3103324
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