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ERK1/2 can feedback-regulate cellular MEK1/2 levels
Signal transduction of the Raf/MEK/ERK pathway is regulated by various feedback mechanisms. Given the greater molar ratio between Raf-MEK than between MEK-ERK in cells, it may be possible that MEK1/2 levels are regulated to modulate Raf/MEK/ERK activity upon pathway stimulation. Nevertheless, it has...
Gorde:
| Argitaratua izan da: | Cell Signal |
|---|---|
| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540659/ https://ncbi.nlm.nih.gov/pubmed/26163823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.07.003 |
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