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Effector Phenotype of Plasmodium falciparum–Specific CD4(+) T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations
Background. Mechanisms mediating immunity to malaria remain unclear, but animal data and experimental human vaccination models suggest a critical role for CD4(+) T cells. Advances in multiparametric flow cytometry have revealed that the functional quality of pathogen-specific CD4(+) T cells determin...
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Publicado no: | J Infect Dis |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539911/ https://ncbi.nlm.nih.gov/pubmed/25646355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv054 |
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