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Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy

BACKGROUND: The stability of the human immunodeficiency virus type 1 (HIV-1) reservoir and the contribution of cellular proliferation to the maintenance of the reservoir during treatment are uncertain. Therefore, we conducted a longitudinal analysis of HIV-1 in T-cell subsets in different tissue com...

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Publicado en:J Infect Dis
Main Authors: von Stockenstrom, Susanne, Odevall, Lina, Lee, Eunok, Sinclair, Elizabeth, Bacchetti, Peter, Killian, Maudi, Epling, Lorrie, Shao, Wei, Hoh, Rebecca, Ho, Terence, Faria, Nuno R., Lemey, Philippe, Albert, Jan, Hunt, Peter, Loeb, Lisa, Pilcher, Christopher, Poole, Lauren, Hatano, Hiroyu, Somsouk, Ma, Douek, Daniel, Boritz, Eli, Deeks, Steven G., Hecht, Frederick M., Palmer, Sarah
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539896/
https://ncbi.nlm.nih.gov/pubmed/25712966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv092
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