Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy

BACKGROUND: The stability of the human immunodeficiency virus type 1 (HIV-1) reservoir and the contribution of cellular proliferation to the maintenance of the reservoir during treatment are uncertain. Therefore, we conducted a longitudinal analysis of HIV-1 in T-cell subsets in different tissue com...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: von Stockenstrom, Susanne, Odevall, Lina, Lee, Eunok, Sinclair, Elizabeth, Bacchetti, Peter, Killian, Maudi, Epling, Lorrie, Shao, Wei, Hoh, Rebecca, Ho, Terence, Faria, Nuno R., Lemey, Philippe, Albert, Jan, Hunt, Peter, Loeb, Lisa, Pilcher, Christopher, Poole, Lauren, Hatano, Hiroyu, Somsouk, Ma, Douek, Daniel, Boritz, Eli, Deeks, Steven G., Hecht, Frederick M., Palmer, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539896/
https://ncbi.nlm.nih.gov/pubmed/25712966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv092
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