The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time

The source and dynamics of persistent HIV-1 during long-term combinational antiretroviral therapy (cART) are critical to understanding the barriers to curing HIV-1 infection. To address this issue, we isolated and genetically characterized HIV-1 DNA from naïve and memory T cells from peripheral bloo...

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Detalhes bibliográficos
Main Authors: Josefsson, Lina, von Stockenstrom, Susanne, Faria, Nuno R., Sinclair, Elizabeth, Bacchetti, Peter, Killian, Maudi, Epling, Lorrie, Tan, Alice, Ho, Terence, Lemey, Philippe, Shao, Wei, Hunt, Peter W., Somsouk, Ma, Wylie, Will, Douek, Daniel C., Loeb, Lisa, Custer, Jeff, Hoh, Rebecca, Poole, Lauren, Deeks, Steven G., Hecht, Frederick, Palmer, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870728/
https://ncbi.nlm.nih.gov/pubmed/24277811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308313110
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