CD4(+) T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

HIV persists in a small pool of latently infected cells despite antiretroviral therapy (ART). Identifying cellular markers expressed at the surface of these cells may lead to novel therapeutic strategies to reduce the size of the HIV reservoir. We hypothesized that CD4(+) T cells expressing immune c...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Fromentin, Rémi, Bakeman, Wendy, Lawani, Mariam B., Khoury, Gabriela, Hartogensis, Wendy, DaFonseca, Sandrina, Killian, Marisela, Epling, Lorrie, Hoh, Rebecca, Sinclair, Elizabeth, Hecht, Frederick M., Bacchetti, Peter, Deeks, Steven G., Lewin, Sharon R., Sékaly, Rafick-Pierre, Chomont, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944956/
https://ncbi.nlm.nih.gov/pubmed/27415008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005761
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