CD4(+) T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

HIV persists in a small pool of latently infected cells despite antiretroviral therapy (ART). Identifying cellular markers expressed at the surface of these cells may lead to novel therapeutic strategies to reduce the size of the HIV reservoir. We hypothesized that CD4(+) T cells expressing immune c...

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Publicado en:PLoS Pathog
Autores principales: Fromentin, Rémi, Bakeman, Wendy, Lawani, Mariam B., Khoury, Gabriela, Hartogensis, Wendy, DaFonseca, Sandrina, Killian, Marisela, Epling, Lorrie, Hoh, Rebecca, Sinclair, Elizabeth, Hecht, Frederick M., Bacchetti, Peter, Deeks, Steven G., Lewin, Sharon R., Sékaly, Rafick-Pierre, Chomont, Nicolas
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944956/
https://ncbi.nlm.nih.gov/pubmed/27415008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005761
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