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An Enhanced Throughput Method for Quantification of Sulfur Mustard Adducts to Human Serum Albumin via Isotope Dilution Tandem Mass Spectrometry

Here we report an enhanced throughput method for the diagnosis of human exposure to sulfur mustard (HD). A hydroxyethylthioethyl (HETE) ester adducted tripeptide, produced by pronase digestion of human serum albumin, was selected as the quantitative exposure biomarker. Cibacron Blue enrichment was d...

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Détails bibliographiques
Publié dans:J Anal Toxicol
Auteurs principaux: Andacht, Tracy M., Pantazides, Brooke G., Crow, Brian S., Fidder, Alex, Noort, Daan, Thomas, Jerry D., Blake, Thomas A., Johnson, Rudolph C.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539155/
https://ncbi.nlm.nih.gov/pubmed/24201816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jat/bkt088
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