An Enhanced Throughput Method for Quantification of Sulfur Mustard Adducts to Human Serum Albumin via Isotope Dilution Tandem Mass Spectrometry

Here we report an enhanced throughput method for the diagnosis of human exposure to sulfur mustard (HD). A hydroxyethylthioethyl (HETE) ester adducted tripeptide, produced by pronase digestion of human serum albumin, was selected as the quantitative exposure biomarker. Cibacron Blue enrichment was d...

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Detalhes bibliográficos
Publicado no:J Anal Toxicol
Main Authors: Andacht, Tracy M., Pantazides, Brooke G., Crow, Brian S., Fidder, Alex, Noort, Daan, Thomas, Jerry D., Blake, Thomas A., Johnson, Rudolph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539155/
https://ncbi.nlm.nih.gov/pubmed/24201816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jat/bkt088
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