CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.

To study the role of B-cell antigen CD40 in immune responses, mouse embryonic stem (ES) cells in which both copies of the gene encoding CD40 had been disrupted by homologous recombination were injected in RAG-2 (recombination-activating gene-2)-deficient blastocysts to generate chimeras in which all...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Castigli, E, Alt, F W, Davidson, L, Bottaro, A, Mizoguchi, E, Bhan, A K, Geha, R S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45391/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7527552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12135
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