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The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function
Poly (ADP-ribose) is synthesized at DNA single-strand breaks and can promote the recruitment of the scaffold protein, XRCC1. However, the mechanism and importance of this process has been challenged. To address this issue, we have characterized the mechanism of poly (ADP-ribose) binding by XRCC1 and...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538820/ https://ncbi.nlm.nih.gov/pubmed/26130715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv623 |
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